In response to the global educational reform we have developed a new education paradigm, the Global Morfosis paradigm which has been implemented at the American Community Schools of Athens (ACS Athens) Greece for the past decade. This dynamic paradigm consists of three inseparable, interconnected, and interrelated components: the Educational Philosophy of Morfosis (Μορφωση), the i2Flex Delivery Methodology, and the Aristeia (Αριστεια) Leadership Approach. Morfosis is defined within the 21st century framework, as a holistic, meaningful, and harmonious educational experience, guided by ethos (Gialamas, 2014). The vehicle to implement Morfosis, is the i2Flex (isquareFlex), a non-traditional learning methodology that draws on the fundamentals of blended learning, and integrates face-to-face and technology-supported instruction with faculty-guided and independent student learning, aiming at developing higher order cognitive skills within a flexible and inspiring learning design (Avgerinou, 2104). The Aristeia Leadership approach is defined by its two essential components (a) the establishment of an Authentic Leadership Identity (ALI), and (b) the creation of a Collective Leadership-Partnership Approach (CPA) (Gialamas, Pelonis, & Medeiros, 2014).